Natural Products Core and Repository
A primary goal of the Natural Products Core is to compile a repository of natural products as an enabling resource for UK investigators involved in lead discovery and development. This repository derives from a range of sources and includes novel microbial natural products discovered from unique environments across the Commonwealth as well as natural product analogs generated via pathway engineering and/or chemo-enzymatic diversification. The repository is available in a convenient screenable format and, for suitable projects, library members can also be provided on larger scale for medicinal chemistry, mechanistic studies, in vivo assessment or development activities. The CPRI is working to highlight and foster the wealth of natural product-based drug discovery expertise and technologies on the UK campus via sponsorship of the annual UK Natural Products Consortium Symposium.
- HT cell-based screens
- BMG FLUOstar plate readers
- Biomek NXp robotics liquid handling system
- Enzo and UK natural products libraries in screenable format
The Natural Products Core welcomes inquiries from UK investigators interested in exploring the potential of novel natural products within the context of emerging research partnerships and collaborations. For more information and to request services, please contact us.