Heidi Mansour - Ph.D.
Dr. Mansour's research focuses on the application of interfacial phenomena and biocolloidal chemistry in the design of advanced drug delivery self-assembly systems and development of pulmonary inhalation aerosols for targeted lung drug delivery (pulmonary disease treatment) and for novel needle-free vaccine inhalation aerosol delivery (pulmonary disease prevention) as multifunctional microparticles and nanoparticles.
She earned a B.S. in pharmacy (1996) and a Ph.D. in pharmaceutical sciences (2003) from the University of Wisconsin at Madison. Dr. Mansour recently was honored during the 2007 American Association of Pharmaceutical Scientists annual meeting in San Diego, receiving the PhRMA Postdoctoral Fellow Award in Pharmaceutics and the AAPS Postdoctoral Fellow Award for research excellence.
Prior to her appointment at UK, she was an Instructor (both in the Graduate and Pharm.D. Programs) and a postdoctoral fellow at the University of North Carolina at Chapel Hill, School of Pharmacy, in the Division of Molecular Pharmaceutics, receiving the 2007 UNC-Chapel Hill Postdoctoral Award for Research Excellence from the Office of the Vice Chancellor.
Selected Honors
- UNC-Chapel Hill Vice Chancellor’s Post-Doctoral Scholar Award in Research Excellence, 2007-2008
- American Association of Pharmaceutical Scientists (AAPS) Post-Doctoral Fellow Award in Research Excellence, 2007
- World Academy of Science, Engineering, and Technology: Scientific Technical Committee on Biological, Biomedical, and Sciences, Elected Member, 2007
- PhRMA Foundation Post-Doctoral Fellow Award in Pharmaceutics, 2007
- National Institutes of Health (NIH)-UNC-Chapel Hill Regional Training Award Scholar, 2007
- Walter F. Enz Award in Research Excellence in the Pharmaceutical Sciences, Pharmacia Global Pharmaceutical Sciences, 2001
- PhRMA Foundation Advanced Pre-Doctoral Fellow Award in Pharmaceutics, 2000-2002
- AFPE Pre-Doctoral Fellow Award in Pharmaceutics, 1999-2001
- Merck Award in Excellence in Pharmacy, 1996
- Rho Chi Pharmaceutical Honor Society Award for Academic Excellence, 1994
- University of Wisconsin-Madison Chemistry Enrichment Award, 1992
- Wisconsin Academic Excellence Scholar, 1991-1995
- Rho Chi Pharmaceutical Honor Society, Elected Member
- Golden Key International Honor Society, Elected Member
- Phi Kappa Phi National Honor Society, Elected Member
- Phi Eta Sigma National Honor Society, Elected Member
Selected Publications
- Mansour, H.M. It's Only Natural: Using Polymers in Drug Delivery. Pharmaceutical Technology (2009) 33 (1) January: 1-2.
- Hickey, A.J. and Mansour, H.M. Volume 2, Chapter 5: Delivery of Drugs by the Pulmonary Route. Modern Pharmaceutics Volume 2: Applications and Advances, Drugs and the Pharmaceutical Sciences Series, Florence, A.T., Siepmann, J. (Editors), Fifth Edition, Taylor & Francis, Inc., New York, (2009): 191-219.
- Mansour H.M., Damodaran S., and Zografi G. Characterization of the In Situ Structural and Interfacial Properties of the Cationic Hydrophobic Heteropolypeptide, KL4, in Lung Surfactant Bilayer and Monolayer Models at the Air-Water Interface: Implications for Pulmonary Surfactant Delivery. Molecular Pharmaceutics (2008) 5 (5) October 6: 681-695. [pdf]
- Hickey, A.J. and Mansour, H.M. Book Chapter 44: Formulation Challenges of Powders for the Delivery of Small Molecular Weight Molecules as Aerosols. Modified-Release Drug Delivery Technology, Drugs and the Pharmaceutical Sciences Series, Rathbone, M. J., Hadgraft, J., Roberts, M.S., Lane, M.E, (Editors), Second Edition, Informa Healthcare, New York, (2008) pp. 573-602.
- Xu, Z., Mansour, H.M., Mulder, T., McLean, R., Langridge, J., and Hickey, A.J. Comparative Dispersion Study of Dry Powder Aerosols of Albuterol Sulfate/Lactose Monohydrate and Cromolyn Sodium/Lactose Monohydrate Delivered by Standardized Entrainment Tubes. Respiratory Drug Delivery (2008) 3: 897-900. [pdf]
- Mansour, H.M. and Hickey, A.J. Raman Characterization and Chemical Imaging of Biocolloidal Self-Assemblies, Drug Delivery Systems, and Pulmonary Inhalation Aerosols. A Review. AAPS PharmSciTech (2007) 8 (4) November 30: Article 99:E1-E16. [pdf]
- Hickey, A.J., Mansour, H.M., et al. Physical Characterization of Component Particles Included in Dry Powder Inhalers: II. Dynamic Characteristics. (Invited Paper). Journal of Pharmaceutical Sciences: Special Issue David Grant Dedicated Issue (2007) 96 (5) May: 1302-1319. [pdf]
- Hickey, A.J., Mansour, H.M., et al. Physical Characterization of Component Particles Included in Dry Powder Inhalers: I. Strategy Review and Static Characteristics. (Invited Paper). Journal of Pharmaceutical Sciences: Special Issue David Grant Dedicated Issue (2007) 96 (5) May: 1282-1301. [pdf]
- Mansour, H.M. and Zografi G. Relationships Between Equilibrium Spreading Pressure and Phase Equilibria of Phospholipid Bilayers and Monolayers at the Air-Water Interface. Langmuir (2007) 23 (7) March 27: 3809-3819. [pdf]
- Mansour, H.M. and Zografi G. The Relationship Between Water Vapor Absorption and Desorption by Phospholipids and Bilayer Phase Transitions. Journal of Pharmaceutical Sciences (2007) 96 (2) February: 377-396. [pdf]
- Mansour H., Wang D.-S., Chen C.-S., and Zografi G. Comparison of Bilayer and Monolayer Properties of Phospholipid Systems Containing Dipalmitoylphosphatidylglycerol and Dipalmitoylphosphatidylinositol. Langmuir (2001) 17 (21) October 16: 6622-6632. [pdf]

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