Elimination-Bismuth (Bi)

Elimination – Bismuth (Bi)

Water-soluble Bi species were excreted more rapidly than Bi species suspended or dissolved in oil. For example, 82.2% of an aqueous solution of bismuth thioglycollate was excreted in four days compared to 1.9% of an oil suspension of bismuth oleate (Kolmer et al., 1939).
Approximately 90% of absorbed Bi is excreted in the urine within 24 hours. The rate is proportional to the solubility of the Bi species.
The contribution of the urinary and fecal route to Bi elimination has not been well determined. It may be Bi species dependent (Slikkerveer and de Wolff, 1996).